By Howard H. Weetall (auth.), George G. Guilbault, Marco Mascini (eds.)
On might 4-8, 1987, a NATO complex learn Workshop at the Analytical makes use of of Immobilized organic Compounds was once held in Florence, Italy. The Director of the Workshop was once Professor George G. Guilbault of the college of latest Orleans, and the Co-Director used to be Professor Marco Mascini of the college of Florence It vas the aim of this assembly to gather scientists from all NATO international locations with an curiosity in immobilized organic compounds. to debate - equipment of immobilization - homes of immobilized compounds - enzyme electrodes and biosensors - optical units using immobilized enzymes - microbial sensors and medical makes use of of immobilized enzymes - circulation injection research utilizing enzymes - immobilized organic compounds in chemical security detection - pharmaceutical research - makes use of in business research - enzyme reactors - pollution detectors - immunosensors - scientific makes use of and functions - strong country and FET sensors ambitions to be completed by way of the convention have been - to allow an alternate of perspectives and adventure in some of these parts - to check and significantly verify the state of the art in those fields - to set directions for destiny learn and determine collaborative tasks among scientists in NATO laboratories within the above parts. Thirty-seven lectures got through 36 audio system in the entire above areas.
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Extra info for Analytical Uses of Immobilized Biological Compounds for Detection, Medical and Industrial Uses
Chem .. 18 (1-2): 343. 10. , 1984, Proc. IDeeting Qn Radigtion Proessina • San Diego. STRUCTURAL AND TRANSPORT PROPERTIES OF POLYMERIC CARRIERS FOR BIOA6E:NTS AND IMMOBILIZATION TECHNIOUES AND THEIR APPLICATIONS Erhan Piskin Hacettepe University, Chemical Engineering Department, Ankara, Turkey ABSTRACT: A wide variety of biological materlals, are incorporated into or onto a carrIer, generally a polymeric material, for a wide variety uses. Biotechnology utilizes immobilized enzymes or microorgamsms for the production of chemicals and many important pharmaceuticals Bioactive agent-carrier composites are employed in clinical medicine for treating many diseases including enzyme deficiencies, autoimmune diseases, etc.
In reservoir systems, a core of agent is surrounded by a polymer film, and diffusion of the agent through this film is the rate-controlling step. These systems include membranes, micro-to macrocapsules, hollow fibers and many other forms. In matrix systems, bioagent is dissolved or throughly dispersed in a polymer matrix. The rate limiting step of these devices may be pure diffusion of the agent (diffusion controlled systems), chemical reaction at the continuously dep leted interface between the polymer and the dissolution medium (chemically controlled systems), or countercurrent diffusion of the agent and the dissolution medium in the polymer (swelling controlled systems).
Bioagents may also be dissolved or dispersed in suitable monomer or monomer mixtures and may then be shaped by following a proper polymerization procedure. 3. APPLICATIONS OF BIOAGENT -POLYMER COMPOSITES A wide variety of bioactive agents (see Table IV) are incorporated onto several solid supports, or entrapped into different matrices, for many diverse applications (see Table V). Table IV. Examples of Bioactive Agents. Aminoacids Antibacterial Agents Antibiotics Antibodies Anticancer Agents Antigens Cell Extracts Chemicals DNA or RNA Sequences Drugs Living or Dead Cells Microorganisms Peptide Sequences Tissue Slices Others Table V.